Deep learning reveals a systems perspective on the origin and evolution of insect wings

The origin and evolutionary mechanisms of insect wings are important and long-standing scientific questions in evolutionary biology. Although some key genes related to wing formation have been identified, there is still a lack of systematic explanation of the regulatory mechanisms of these genes in different insect taxa. In this study, we analyzed the molecular regulatory mechanisms of insect wing origin and evolution by deep learning techniques. We constructed models based on Bidirectional Gated Recurrent Unit and Attention Mechanisms, integrated genomic protein sequence information from 119 species, and successfully identified a series of highly weighted genes that may be involved in the origin and evolution of insect wings. The results suggest that the origin and evolution of insect wings may be a complex systematic engineering. In summary, this study not only reveals the molecular mechanism of insect wing development, but also reveals the potential value of deep learning in complex biology research.

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29553629.v1
Primary Topic
Developmental Biology and Gene Regulation
Type
article
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Deep learning reveals a systems perspective on the origin and evolution of insect wings

Figshare
Developmental Biology and Gene Regulation
article

Deep learning reveals a systems perspective on the origin and evolution of insect wings

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Abstract

The origin and evolutionary mechanisms of insect wings are important and long-standing scientific questions in evolutionary biology. Although some key genes related to wing formation have been identified, there is still a lack of systematic explanation of the regulatory mechanisms of these genes in different insect taxa. In this study, we analyzed the molecular regulatory mechanisms of insect wing origin and evolution by deep learning techniques. We constructed models based on Bidirectional Gated Recurrent Unit and Attention Mechanisms, integrated genomic protein sequence information from 119 species, and successfully identified a series of highly weighted genes that may be involved in the origin and evolution of insect wings. The results suggest that the origin and evolution of insect wings may be a complex systematic engineering. In summary, this study not only reveals the molecular mechanism of insect wing development, but also reveals the potential value of deep learning in complex biology research.

Figshare
Openalex Percentile: Top 61%
Developmental Biology and Gene Regulation
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Deep learning reveals a systems perspective on the origin and evolution of insect wings · Figshare (2025) | TGRS Research Map | TGRS