Additional file 1 of A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model

Additional file 1. Figure S1: Comparison of different siPOOL concentrations. Figure S2: Quantification of αSyn total intracellular and extracellular levels upon knockdown of SX5. Figure S3: Investigation of the effect of the knockdown of other SNXs. Figure S4: Brefeldin A (BFA) treatment led to Golgi fragmentation and cytotoxicity. Figure S5: The figure shows a version of panel c of panel 6 from the main manuscript with inclusion of the red channel that shows the signal of labeled αSyn. Table S1: Antibodies used for Western blot analysis. Table S2: Antibodies used for immunocytochemistry. Supplementary methods of Brefeldin A treatment.

Institutions

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29219838.v1
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Additional file 1 of A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model

Figshare
Parkinson's Disease Mechanisms and Treatments
article

Additional file 1 of A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model

article en

Abstract

Additional file 1. Figure S1: Comparison of different siPOOL concentrations. Figure S2: Quantification of αSyn total intracellular and extracellular levels upon knockdown of SX5. Figure S3: Investigation of the effect of the knockdown of other SNXs. Figure S4: Brefeldin A (BFA) treatment led to Golgi fragmentation and cytotoxicity. Figure S5: The figure shows a version of panel c of panel 6 from the main manuscript with inclusion of the red channel that shows the signal of labeled αSyn. Table S1: Antibodies used for Western blot analysis. Table S2: Antibodies used for immunocytochemistry. Supplementary methods of Brefeldin A treatment.

Figshare
University of Veterinary Medicine Hannover, Foundation (DE), German Center for Neurodegenerative Diseases (DE), Medizinische Hochschule Hannover (DE), Munich Cluster for Systems Neurology (DE), Max Planck Institute of Molecular Cell Biology and Genetics (DE), Ludwig-Maximilians-Universität München (DE)
Good health and well-being
Openalex Percentile: Top 43%
Parkinson's Disease Mechanisms and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.