Additional file 2 of Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice

Supplementary Material 2: Supplementary Fig. 2 The L19-targeted antibody specifically hits EDB-FN1 of human tumor tissues. L19-targeted antibody in IgG1 format specifically target EDB-FN1 (Green) in human PDAC tumor tissues, while KSF antibody (specific for hen egg lysozyme, an irrelevant antigen) was used as negative CTR.

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Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.28157708
Primary Topic
Immunotherapy and Immune Responses
Type
article
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article

Additional file 2 of Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice

Figshare
Immunotherapy and Immune Responses
article

Additional file 2 of Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice

article en

Abstract

Supplementary Material 2: Supplementary Fig. 2 The L19-targeted antibody specifically hits EDB-FN1 of human tumor tissues. L19-targeted antibody in IgG1 format specifically target EDB-FN1 (Green) in human PDAC tumor tissues, while KSF antibody (specific for hen egg lysozyme, an irrelevant antigen) was used as negative CTR.

Figshare
Università Cattolica del Sacro Cuore (IT), University of Verona (IT), Agostino Gemelli University Polyclinic (IT), ETH Zurich (CH), Philogen (Italy) (IT), Philochem (Switzerland) (CH), University of the Sacred Heart (JP)
Good health and well-being
Openalex Percentile: Top 52%
Immunotherapy and Immune Responses
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