Additional file 1 of HELLS is required for maintaining proper DNA modification at human satellite repeats

Additional file 1. Fig. S1: Characterization of HELLS KO and DNMT mutant DNA methylation landscapes. Fig. S2: Characterization of HELLS KO and DNMT mutant DNA methylation levels at satellite repeats. Fig. S3: HELLS is indispensable for maintenance of DNA methylation at satellite repeats. Fig. S4: Chromatin and transcriptional features of HELLS KO iPSCs. Fig. S5: Overview of delta DNA methylation between WT and HELLS KO across individual chromosomes. Fig. S6: HELLS is not required to remodel enhancer landscapes essential for early embryonic lineage formation. Fig. S7: Gating strategy for sorting three-germ layer differentiated human iPSCs.

Institutions

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29595505
Primary Topic
Chromosomal and Genetic Variations
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Additional file 1 of HELLS is required for maintaining proper DNA modification at human satellite repeats

Figshare
Chromosomal and Genetic Variations
article

Additional file 1 of HELLS is required for maintaining proper DNA modification at human satellite repeats

article en

Abstract

Additional file 1. Fig. S1: Characterization of HELLS KO and DNMT mutant DNA methylation landscapes. Fig. S2: Characterization of HELLS KO and DNMT mutant DNA methylation levels at satellite repeats. Fig. S3: HELLS is indispensable for maintenance of DNA methylation at satellite repeats. Fig. S4: Chromatin and transcriptional features of HELLS KO iPSCs. Fig. S5: Overview of delta DNA methylation between WT and HELLS KO across individual chromosomes. Fig. S6: HELLS is not required to remodel enhancer landscapes essential for early embryonic lineage formation. Fig. S7: Gating strategy for sorting three-germ layer differentiated human iPSCs.

Figshare
University of Potsdam (DE), Max Planck Institute for Molecular Genetics (DE), Freie Universität Berlin (DE)
Life in Land
Openalex Percentile: Top 69%
Chromosomal and Genetic Variations
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.