Additional file 4 of Merging metabolomics and genomics provides a catalog of genetic factors that influence molecular phenotypes in pigs linking relevant metabolic pathways

Additional file 4: Text S1. Detail on quantitative real time PCR and western blotting analyses of KMO. Text S2. Relationships between heritability estimates of some metabolites in pigs and their chemical structures. Text S3. Comparative information on candidate genes between humans and pigs. Text S4. Identification and annotation of variants from whole genome resequencing data. Text S5. Evaluation of KMO mutations in relation to its protein sequence and structure. Text S6. Inclusion of the genetic effect in the Gaussian Graphical Model (GGM) construction. Text S7. Merging GGM and GWAS results.