Two rare C14-C15 chemical bond-breaking 7/5/5 skeleton schinortriterpenoids and their neuroprotective activities of against CORT-induced apoptosis of PC12 from the <i>Schisandra chinensis</i> leaves and stems
Two rare C14-C15 chemical bond-breaking 7/5/5 skeleton schinortriterpenoids (SNTs), Wuweizinortriters A and B (1–2) were successfully isolated from the ethanol extracts of the leaves and stems of <i>Schisandra chinensis.</i>, the determination of their structures was achieved by using NMR, MS, UV, and carbon spectrum calculation. Wuweizinortriters A and B (25 μM) moderately protected PC12 cells from CORT-induced apoptosis, with the viability increasing by 18.02% and 20.33% respectively, compared to the model group.
Publication Details
- Journal
- Figshare
- Published
- 2025-01-01
- DOI
- https://doi.org/10.6084/m9.figshare.28646380.v1
- Primary Topic
- Plant-derived Lignans Synthesis and Bioactivity
- Type
- article
- Field-Weighted Citation Impact
- 0.00