Atg7 KO leads to accumulation of mitochondria in mouse adipose tissue.

(A-B) Western blotting (panel A) and densitometric (panel B) analyses of mitochondrial biogenesis markers (Pgc1α and Pgc1β) and mitochondrial content marker (COXIV) in visceral adipose tissues from control and ad7KO male mice. n=6. (C-D) Western blotting (panel C) and densitometric (panel D) analyses of mitophagy markers (Pink1, Bnip3, and Fundc1) in visceral adipose tissues from control and ad7KO male mice. n=6. (E-F) Western blotting (panel E) and densitometric (panel F) analyses of mitochondrial dynamics proteins (Drp1, pDrp1-S637, and OPA1) in visceral adipose tissues from control and ad7KO male mice. n=6. *p < 0.05, **p < 0.01; ***p<0.001.