Additional file 2 of Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer

Additional file 2 (Fig. S2 Validation screen of top five QPOP-ranked drug combinations. a Single drug and combination dose response curves of QPOP-derived top-ranking drug pairs across (i) WT and (ii) RR FaDu, with accompanying b Fa-CI (fraction affected-combination index) plot. Combination indices of log(CI) <0 across a range of effect sizes (Fa) is indicative of a synergistic interaction. Data presented as means ± SD of two technical replicates.)