Additional file 1 of The phosphatase PPM1F, a negative regulator of integrin activity, is essential for embryonic development and controls tumor cell invasion

Additional file 1: Figure S1 indicates similar size and brain histology of PPM1F ± mice compared to their wildtype littermates. Figure S1: Related to Fig. 3. Ppm1f ± adult mice have similar brain size and brain histology compared to their wildtype littermates. (A) Individual brain homogenates from 3–4 months old male wildtype PPM1 + / + and PPM1F ± mice were probed by Western blotting with antibodies against murine PPM1F (upper panel) or tubulin (lower panel). (B) Body weight of mice as in (A). Shown is mean ± s.e.m; n = 5; unpaired t-test, ns: not significant. (C) Brains of mice in (A) were isolated, weighted, and photographed. Scale bar: 1 cm (D) Coronal brain sections of PPM1 + / + and PPM1F ± mice were stained with cresyl violet. Lower panels show magnifications of the indicated, boxed cortical areas.