Additional file 3 of The role of B12 deficiency and methionine synthase in methionine-dependent cancer cells

Supplementary Material 3: Figure 3. Gene expression patterns in parental and revertant cells. a, Non-redundant gene ontologypathways enriched in cluster 2, visualized as UMap projection of semantic similarity. Size of circles represent pathway over-representation score. b, S-plot of metastatic signature versus ratio of gene expression in cluster 0 over cluster 1. c, p-values for expression signature match against human 1,355 cell types in cluster 0 and cluster 1. Selected cell types are highlighted. d, Ratio of gene expression levels in D21 over D0 cells for selected genes involved in B12 transport and metabolism.