Evaluation of the catalytic and in-vitro anticancer potential of Gold nanoparticles synthesized using clammy cherry (Cordia Obliqua Willd)

The synthesis of metal nanoparticles using environmentally friendly materials like fruit extracts offers the benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications. The phytogenic synthesis can be conducted at convenient ease under microwave exposure. Here, through a microwave-assisted, fast, and cost-effective approach, monodispersed, spherical gold nanoparticles (AuNPs) with outstanding catalytic efficiency and anticancer activity were successfully synthesized using the extract of clammy cherry (Cordia Obliqua Willd) fruit. UV-Visible spectroscopic analysis, SEM, and HRTEM analysis have been used to characterize the prepared AuNPs. The electronic spectrum investigations have revealed that the MW power, length of exposure, gold ion concentration, and content of the cherry extract had a substantial impact on the rate of production, size, and surface plasmon absorption of AuNPs. According to TEM examinations, AuNPs are crystalline and spherical in shape, with a mean size of 11.7 nm. Anticancer activity of the stabilized AuNPs studied against Dalton's lymphoma Ascites cells confirmed that the stabilized AuNPs were highly effective for the apoptosis of cancer cells selectively. Furthermore, the AuNPs' catalytic efficiency in reducing hazardous organic pollutants viz. methyl orange (MO), methylene blue (MB), and methyl red (MR), 2-nitrophenol (2-NP) and 4-nitrophenol (4-NP), with borohydride-aided reduction proved appealing for environmental pollution remediation applications.