AA manuscript

Data related to AA manuscript Data to reproduce findings in the manuscript "Single-cell characterization of immune aplastic anemia reveals convergence of adaptive and innate immunity". The folder contains: 1) Processed scRNA+TCRαβ-seq data as Seurat-objects, including * "discovery" object with AA and healthy samples (Fig. 1) * "pan-heme" NK cell object with AA, healthy, and other hematological disorder samples (Fig. 2) * "pan-heme" CD8+ cell object with AA, healthy, and other hematological disorder samples (Fig. 2) * "pan-heme" CD4+ cell object with AA, healthy, and other hematological disorder samples (Fig. 2) * "co-culture" demultiplexed CD45+ object from all different co-culture conditions (Fig. 5&6) * "co-culture" HSPC object from all different co-culture conditions (Fig. 5) * "co-culture" NK cell object from all different co-culture conditions (Fig. 5) * "co-culture" CD8+ cell object from all different co-culture conditions (Fig. 6) 2) TCRβ-seq samples profiled in this study, including * AA * PNH * MDS * T-LGLL * IBMFS * ICUS/CHIP 3) scTCRαβ-seq data from AA BM samples 4) Olink cytokine data from AA and healthy samples Please see manuscript and Github for further details. Other accession codes are in the manuscript.