MODERN CONCEPTS OF EPIDEMIOLOGY, ETIOPATHOGENESIS, DIAGNOSIS, CLINICAL PICTURE AND TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS

The problem of cerebral circulatory disorders, which are based on vascular lesions of the nervous system, continues to be the most important and priority in modern clinical medicine (Vilensky B.S., 2008; Piradov M.A., 2010; Gusev E.I., 2012; Kamchatnov P.P., 2012). Stroke ranks second in the structure of mortality worldwide and is the leading cause of disability in economically developed countries ( Gudkova V.V., Stakhovskaya L.V., 2011; Gusev E.I., Skvortsova V.I., 2012; Murray S.J.L., Lopez AD, 2008). Currently, much attention is paid to the study of the pathogenetic mechanisms of cerebrovascular pathology (CVP). The main controllable and uncontrollable risk factors (RF) of cerebrovascular diseases have been established, however, other causes of development of vascular pathology of the brain (various clinical forms of vasculopathy and vasculitis) remain less studied.