Effect of Chemotherapy on Protein Level of Under Treatment Cancer Sufferers

Abstract : Introduction: Cancer staging is an important aspect of cancer management and directly affects the treatment plan of the patient. There are several protein tumour markers that helps in the diagnosis as well as prognosis of cancer patients. Aim: The current study aims to evaluate the total protein value from the serum samples of selected cancer patients and see any pattern with different stages of patients. Materials & Method: Total proteins were measured by IR-VS spectroscopy method and compared in different patients. Result: The spectrophotometric analysis of the collected serum samples showed that chemotherapy induced total protein loss is associated with dysregulation in serum proteins and electrolytes. Total protein is a significant marker that can help determine the tumour staging in cancer patients and thus can act as a prognostic marker also. It is a simple, non-invasive and cost effective method of analysis.