Formulation & Evaluation of Polyherbal Anti-Microbial Ointment of Blumea Lacera and Moringa Oleifera

The present study aimed to formulate and evaluate a polyherbal ointment incorporating Blumea lacera and Moringa oleifera extracts for antimicrobial activity. Both plants are traditionally known for their potent therapeutic properties, particularly in wound healing and infection control. Ethanolic extracts of Blumea lacera and Moringa oleifera leaves were prepared and incorporated into a simple ointment base at 4% w/w concentration each, resulting in the F3 formulation. The ointment was evaluated for various physicochemical parameters, including appearance, pH, spreadability and stability. Among all batches, F3 showed superior consistency and uniformity. Antimicrobial activity was assessed using the agar well diffusion method against Staphylococcus aureus and Escherichia coli. The F3 formulation exhibited significant zones of inhibition against both organisms, indicating broad-spectrum antimicrobial potential. The synergistic effect of both herbal extracts contributed to enhanced antimicrobial efficacy, making the formulation a promising natural alternative for topical infections. The study supports the potential of combining Blumea lacera and Moringa oleifera as effective ingredients in herbal ointment development.