A REVIEW OF VITAMIN D IN SPINAL SURGERY

In this review, we discuss the demonstrated value of vitamin D in bone maintenance, fracture resistance, spinal health, and spine surgery outcomes. Despite this, the effect of vitamin D levels in spine surgery has not been well described. Through this review of literature, several conclusions were drawn. First, despite the fact that a high number of spine surgery patients are vitamin D deficient, screening is not commonly performed. Second, adequate vitamin D levels will not be achieved in a majority of these patients without supplementation. Last, inadequate vitamin D levels may increase the risk of pseudarthrosis. Given these findings, we suggest that many patients undergoing spinal surgery could be treated with vitamin D supplementation prior to surgery without the need for confirmatory testing for vitamin D deficiency. This is a more cost-effective method than screening all patients. However, future randomized trials and cost-effectiveness analyses are needed to determine the ultimate effects of vitamin D supplementation on clinical morbidity and surgical outcomes.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-24
DOI
https://doi.org/10.5281/zenodo.15727882
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
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article

A REVIEW OF VITAMIN D IN SPINAL SURGERY

Zenodo (CERN European Organization for Nuclear Research)
Vitamin D Research Studies
article

A REVIEW OF VITAMIN D IN SPINAL SURGERY

article en

Abstract

In this review, we discuss the demonstrated value of vitamin D in bone maintenance, fracture resistance, spinal health, and spine surgery outcomes. Despite this, the effect of vitamin D levels in spine surgery has not been well described. Through this review of literature, several conclusions were drawn. First, despite the fact that a high number of spine surgery patients are vitamin D deficient, screening is not commonly performed. Second, adequate vitamin D levels will not be achieved in a majority of these patients without supplementation. Last, inadequate vitamin D levels may increase the risk of pseudarthrosis. Given these findings, we suggest that many patients undergoing spinal surgery could be treated with vitamin D supplementation prior to surgery without the need for confirmatory testing for vitamin D deficiency. This is a more cost-effective method than screening all patients. However, future randomized trials and cost-effectiveness analyses are needed to determine the ultimate effects of vitamin D supplementation on clinical morbidity and surgical outcomes.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 42%
Vitamin D Research Studies
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A REVIEW OF VITAMIN D IN SPINAL SURGERY · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS