FORMULATION AND EVALUATION OF LINAGLIPTIN NANOPARTICLES LOADED SUBLINGUAL FILM FOR DIABETES MELLITUS

Typically, Diabetes mellitus is a metabolic disorder characterized by the elevation of blood glucose level due to defective or relative deficiency of insulin secretion. This hormone, insulin, is produced by the pancreas. Insulin is like a key that unlocks the door to separate cells from the sugars in our bloodstream. Whereas Type 2 diabetes occurs mainly due to insulin resistance or with relative insulin deficiency The goal is to create Linagliptin SLNs in order to increase the drug's bioavailability and permeability.