Formulation and Evaluation of Herbal Antidiabetic Tea Granules Powder

The goal of the current study was to create, develop, and assess a polyherbal tea granule formulation that combined Aegle marmelos (Belpatra), Momordica charantia (Karela), Tinospora cordifolia (Guduchi), Eugenia jambolana (Jamun), and Stevia rebaudiana (Stevia) for possible antidiabetic benefits. These traditionally used herbs have all demonstrated potential as antidiabetic agents, and their combined effects may be more potent. Nine formulations (F1–F9) with varying herb quantities were made using solvent extraction, and the findings were standardized using HPLC. The optimized formulation (F5) was evaluated for its phytochemical content, antioxidant activity (DPPH, FRAP), antidiabetic activity (in vitro inhibition of α-amylase and α-glucosidase, in vivo streptozotocin-induced diabetic rats), sensory qualities (taste, aroma, color, overall acceptability), and physical attributes (moisture content, bulk density, particle size).

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-20
DOI
https://doi.org/10.5281/zenodo.14891752
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
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article

Formulation and Evaluation of Herbal Antidiabetic Tea Granules Powder

Zenodo (CERN European Organization for Nuclear Research)
Natural Antidiabetic Agents Studies
article

Formulation and Evaluation of Herbal Antidiabetic Tea Granules Powder

article en

Abstract

The goal of the current study was to create, develop, and assess a polyherbal tea granule formulation that combined Aegle marmelos (Belpatra), Momordica charantia (Karela), Tinospora cordifolia (Guduchi), Eugenia jambolana (Jamun), and Stevia rebaudiana (Stevia) for possible antidiabetic benefits. These traditionally used herbs have all demonstrated potential as antidiabetic agents, and their combined effects may be more potent. Nine formulations (F1–F9) with varying herb quantities were made using solvent extraction, and the findings were standardized using HPLC. The optimized formulation (F5) was evaluated for its phytochemical content, antioxidant activity (DPPH, FRAP), antidiabetic activity (in vitro inhibition of α-amylase and α-glucosidase, in vivo streptozotocin-induced diabetic rats), sensory qualities (taste, aroma, color, overall acceptability), and physical attributes (moisture content, bulk density, particle size).

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 45%
Natural Antidiabetic Agents Studies
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