A Review on Analytical Method Development for Drug Sitagliptin

The Sitagliptin offer significant therapeutic benefits in managing type 2 diabetes mellitus (T2DM) and associated cardiovascular risks. The development of accurate, precise, and validated analytical methods is crucial for ensuring their efficacy, safety, and regulatory compliance. This review explores various analytical techniques, including High-Performance Liquid Chromatography (HPLC), Reverse Phase HPLC (RP- HPLC), High-Performance Thin Layer Chromatography (HPTLC), Liquid Chromatography-Mass Spectrometry (LC-MS/MS), and UV spectrophotometry, highlighting their advantages, challenges, and validation parameters.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-22
DOI
https://doi.org/10.5281/zenodo.15263891
Primary Topic
Analytical Methods in Pharmaceuticals
Type
article
Field-Weighted Citation Impact
0.00
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article

A Review on Analytical Method Development for Drug Sitagliptin

Zenodo (CERN European Organization for Nuclear Research)
Analytical Methods in Pharmaceuticals
article

A Review on Analytical Method Development for Drug Sitagliptin

article en

Abstract

The Sitagliptin offer significant therapeutic benefits in managing type 2 diabetes mellitus (T2DM) and associated cardiovascular risks. The development of accurate, precise, and validated analytical methods is crucial for ensuring their efficacy, safety, and regulatory compliance. This review explores various analytical techniques, including High-Performance Liquid Chromatography (HPLC), Reverse Phase HPLC (RP- HPLC), High-Performance Thin Layer Chromatography (HPTLC), Liquid Chromatography-Mass Spectrometry (LC-MS/MS), and UV spectrophotometry, highlighting their advantages, challenges, and validation parameters.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 56%
Analytical Methods in Pharmaceuticals
DOIOpen Access PDFOpenAlex
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A Review on Analytical Method Development for Drug Sitagliptin · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS