Exploring The Cytoprotective Effect of Phyllanthus Emblica (Amla Leaf)

Phyllanthus emblica (amla) leaf extract's cytoprotective ability is assessed in this work using the in vitro MTT test on L929 fibroblast cell lines. This study examines the lesser-known leaf extract of amla for its capacity to maintain cell viability under cytotoxic stress, despite the fruit's well-established therapeutic qualities. High cell viability was sustained at escalating concentrations (20–100 µg/mL), indicating the extract's strong cytoprotective action. A protective effect against oxidative and toxic insults was demonstrated by the cell viability of 72.30 percent at the highest tested concentration of 100 µg/mL Alkaloids, glycosides, flavonoids, tannins, and saponins—all of which are known to support cytoprotection—were verified by phytochemical analysis. These results point to the possibility for amla leaves to be developed as natural therapeutic agents and support their traditional medicinal use.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-05
DOI
https://doi.org/10.5281/zenodo.15601467
Primary Topic
Phytochemistry and Bioactivity Studies
Type
article
Field-Weighted Citation Impact
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article

Exploring The Cytoprotective Effect of Phyllanthus Emblica (Amla Leaf)

Zenodo (CERN European Organization for Nuclear Research)
Phytochemistry and Bioactivity Studies
article

Exploring The Cytoprotective Effect of Phyllanthus Emblica (Amla Leaf)

article en

Abstract

Phyllanthus emblica (amla) leaf extract's cytoprotective ability is assessed in this work using the in vitro MTT test on L929 fibroblast cell lines. This study examines the lesser-known leaf extract of amla for its capacity to maintain cell viability under cytotoxic stress, despite the fruit's well-established therapeutic qualities. High cell viability was sustained at escalating concentrations (20–100 µg/mL), indicating the extract's strong cytoprotective action. A protective effect against oxidative and toxic insults was demonstrated by the cell viability of 72.30 percent at the highest tested concentration of 100 µg/mL Alkaloids, glycosides, flavonoids, tannins, and saponins—all of which are known to support cytoprotection—were verified by phytochemical analysis. These results point to the possibility for amla leaves to be developed as natural therapeutic agents and support their traditional medicinal use.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 50%
Phytochemistry and Bioactivity Studies
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