FEATURES OF MORPHOLOGICAL FORMATION OF KNEE JOINT ELEMENTS IN OFFSPRING DEVELOPED UNDER THE INFLUENCE OF EXPERIMENTAL HYPOTHYROIDISM

Hypothyroidism, and the exact presence of thyroid hormone in the blood in low concentrations leads to the fact that the metabolism in the body gets out of control, as a result of which pathological changes of varying degrees develop. Hypothyroidism is caused by several factors: injuries of a gland, tumors or cystic diseases, disorders of the pituitary-hypothalamic system, defects in the development of the gland, surgical interventions errors, long-term use of antithyroid drugs, etc. The situation with hypothyroidism is common among population, and the deficiency is common in our region. This article describes the morphometric changes in the knee system in early ontogenesis, which was obtained in the study of offspring born from a mother with experimental hypothyroidism during pregnancy. The model of experimental hypothyroidism and the results of the early study show morphofunctional changes in the elements of the knee joint and the generation of this disease.