Toxic Epidermal Necrolysis (TEN) in a Patient with Human Immunodeficiency Virus: Case Report

Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN) is a spectrum of mucocutaneous hypersensitivity reactions. This report details the case of an18-year-old male patient with a history of HIV who developed extensive skin lesions and mucosal involvement after using carbamazepine. The diagnosis was confirmed clinically, and it was treated with intravenous corticosteroids, crystalloid solutions, supportive care, and discontinuation of the implicated drug, resulting in favorable clinical evolution. This case highlights the importance of early recognition of SJS/TEN and immediate withdrawal of the causative agent to improve prognosis.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-01
DOI
https://doi.org/10.5281/zenodo.14958256
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Toxic Epidermal Necrolysis (TEN) in a Patient with Human Immunodeficiency Virus: Case Report

Zenodo (CERN European Organization for Nuclear Research)
Drug-Induced Adverse Reactions
article

Toxic Epidermal Necrolysis (TEN) in a Patient with Human Immunodeficiency Virus: Case Report

article en

Abstract

Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN) is a spectrum of mucocutaneous hypersensitivity reactions. This report details the case of an18-year-old male patient with a history of HIV who developed extensive skin lesions and mucosal involvement after using carbamazepine. The diagnosis was confirmed clinically, and it was treated with intravenous corticosteroids, crystalloid solutions, supportive care, and discontinuation of the implicated drug, resulting in favorable clinical evolution. This case highlights the importance of early recognition of SJS/TEN and immediate withdrawal of the causative agent to improve prognosis.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Maya de las Américas (MX)
Good health and well-being
Openalex Percentile: Top 55%
Drug-Induced Adverse Reactions
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