New antimicrobial surfaces based on silica mesoporous nanoparticles functionalized with bioactive compounds

These coatings based on silica nanoparticles (SMINs) are modified with copper andcarvacrol, an essential oil. The copper ions released from the nanoparticles damagebacteria and viruses by disrupting their cellular structures, while carvacrol enhances thiseffect by breaking down membranes and DNA. Laboratory tests demonstrated thatthese nanocoatings are highly effective: they can eliminate 100% of bacteria such as E.coli and S. aureus within just 5 minutes. Additionally, they significantly reducethepresence of SARS-CoV-2, with over 70% reduction observed after one hour ofcontact. However, theireffectiveness against non-enveloped viruses like MS2 is more limited. Overall, thisinnovative approach offers a promising, eco-friendly solution for creating antimicrobialand antiviral surfaces, contributing to improved hygiene and safety in various settings.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-17
DOI
https://doi.org/10.5281/zenodo.15681042
Primary Topic
Antimicrobial agents and applications
Type
article
Field-Weighted Citation Impact
0.00
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article

New antimicrobial surfaces based on silica mesoporous nanoparticles functionalized with bioactive compounds

Zenodo (CERN European Organization for Nuclear Research)
Antimicrobial agents and applications
article

New antimicrobial surfaces based on silica mesoporous nanoparticles functionalized with bioactive compounds

article en

Abstract

These coatings based on silica nanoparticles (SMINs) are modified with copper andcarvacrol, an essential oil. The copper ions released from the nanoparticles damagebacteria and viruses by disrupting their cellular structures, while carvacrol enhances thiseffect by breaking down membranes and DNA. Laboratory tests demonstrated thatthese nanocoatings are highly effective: they can eliminate 100% of bacteria such as E.coli and S. aureus within just 5 minutes. Additionally, they significantly reducethepresence of SARS-CoV-2, with over 70% reduction observed after one hour ofcontact. However, theireffectiveness against non-enveloped viruses like MS2 is more limited. Overall, thisinnovative approach offers a promising, eco-friendly solution for creating antimicrobialand antiviral surfaces, contributing to improved hygiene and safety in various settings.

Zenodo (CERN European Organization for Nuclear Research)
University of Rome Tor Vergata (IT), Finnish Defence Forces (FI), Institute for Defence Studies and Analyses (IN)
Openalex Percentile: Top 68%
Antimicrobial agents and applications
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