Formulation And Evaluation of Anti-Acne Emulgel of Morus Rubra (Mulberry)And Antibacterial Test Against Staphylococcus Aureus and Propionibacterium Acne Bacteria

Bacterial infections are a global public health concern due to their impact on the morbidity and mortality of various populations. Skin as a route of drug administration is useful for bacterial infection treatment which is a common problem in dermatology. Emulgel is a recently developed drug delivery system which allows for controlled emulsion and gel release for topical applications. Stability can be enhanced by incorporating an emulsion into a gel. In the current investigation, Emulgel containing extract of mulberry was formulated for the management of bacterial skin infections. The extracting procedures were performed with the emulsifying agent’s tween 20 and span 20 to create the required emulsions. Emulgel was made by mixing emulsions with Carbopol 934.The preparation was done and evaluation parameters like pH, physical appearance, stability, spreadability, in vitro drug released study as well as antibacterial properties were checked. The formulation provided results that were acceptable for the tested parameters. The result showed formulation has Better spreadability, stability, and antibacterial properties than the other formulation. From those parameters, it was found that emulgel with leaves extract of Morus rubra (Mulberry) has the potential to treat skin bacterial infections while offering cosmetic advantages.