A Crucial Parameters of Polio Vaccine Include Indications, Mechanism of Action, Administration, Adverse Effects and Contra Indications

Poliomyelitis is a highly infectious viral illness that can result in permanent disability. Global vaccination efforts have decreased in a drastical manner the incidence of polio, bringing the disease to the brink of elimination. Even though the oral polio vaccination has a rare risk of paralysis, it is nonetheless an essential tool in many regions of the world due to its low cost and simplicity of administration. In contrast, the inactivated polio vaccine is used in an exclusive manner in countries along with adequate sanitation infrastructure, including the United States, where the risk of vaccine-derived poliovirus is minimized to the maximum extent.Both oral and inactivated polio vaccines' modes of action, routes of administration, formulations, side effects, and patient eligibility are explained in this activity. Vaccination continues to be a top priority for global public health due to the spread of vaccine-derived poliovirus and the continuous transmission of wild-type polio in Afghanistan and Pakistan. The interprofessional healthcare team plays a crucial role in achieving the eradication aim by guaranteeing mass vaccination and keeping an eye out for side effects.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-23
DOI
https://doi.org/10.5281/zenodo.15718834
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

A Crucial Parameters of Polio Vaccine Include Indications, Mechanism of Action, Administration, Adverse Effects and Contra Indications

Zenodo (CERN European Organization for Nuclear Research)
Viral Infections and Immunology Research
article

A Crucial Parameters of Polio Vaccine Include Indications, Mechanism of Action, Administration, Adverse Effects and Contra Indications

article en

Abstract

Poliomyelitis is a highly infectious viral illness that can result in permanent disability. Global vaccination efforts have decreased in a drastical manner the incidence of polio, bringing the disease to the brink of elimination. Even though the oral polio vaccination has a rare risk of paralysis, it is nonetheless an essential tool in many regions of the world due to its low cost and simplicity of administration. In contrast, the inactivated polio vaccine is used in an exclusive manner in countries along with adequate sanitation infrastructure, including the United States, where the risk of vaccine-derived poliovirus is minimized to the maximum extent.Both oral and inactivated polio vaccines' modes of action, routes of administration, formulations, side effects, and patient eligibility are explained in this activity. Vaccination continues to be a top priority for global public health due to the spread of vaccine-derived poliovirus and the continuous transmission of wild-type polio in Afghanistan and Pakistan. The interprofessional healthcare team plays a crucial role in achieving the eradication aim by guaranteeing mass vaccination and keeping an eye out for side effects.

Zenodo (CERN European Organization for Nuclear Research)
Industry, innovation and infrastructure, Partnerships for the goals
Openalex Percentile: Top 41%
Viral Infections and Immunology Research
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A Crucial Parameters of Polio Vaccine Include Indications, Mechanism of Action, Administration, Adverse Effects and Contra Indications · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS