A CLINICAL EFFICACY OF DIETARY REGIME (MILLETS) IN MADHUMEHA (TYPE-2 DIABETES MELLITUS)

Background: Diabetes Mellitus has turned out to be the considerable silent killer today within the world. Diabetes Mellitus can be correlated with an identical disease delineated in Ayurveda as Madhumeha. Madhumeha is a clinical entity described in Ayurveda under the types of Vataja Prameha, and can be managed conservatively with Modifications in diet, exercise, medication and lifestyle are all important factors in successful treatment of type 2 diabetes and are assimilated into the ancient Indian medicinal practice of Ayurveda. Aim: The aim is to evaluate the efficacy of dietary regime in Madhumeha (Type 2 Diabetes Mellitus) Materials and methods: 50 patients were screened for the assessment from outpatient department (OPD) of Kayachikitsa patients with Diabetes type 2 and on the basis of CRF-1 (Case Report Form 1), Among them 05 were excluded as they were not meeting the inclusion criteria. Total 45 subjects 23 were allocated for intervention in Group A and 22 patients were in Group B. In Group A (Trial Group)- Chandraprabha along with dietary regime was given dosage of 2 tablet ( each 5oomg) twice in a day for 21 days an hour before meal with lukewarm water. In Group B (Comparator Group)-Chandraprabha Vati19 was given dosage of 500 mg twice in a day for 21 days half an hour before meal with lukewarm water . The data in the clinical study was analyzed by applying appropriate statistical methods including Chi-square/ Fisher Exact test for subjective criteria and Student’s paired t-test for objective criteria. Results: After analyzing the data Group A, shown Significant reduction was seen in raised FBS Level in first week (p value <0.05) and last 14 days of treatment and the mean PPBS was reduced significantly at Day 7, Day 14 and Day 21 (p<0.05). In Group B, the mean FBS was reduced significantly between Day 7 and Day 14 (p<0.05) & Baseline to Day 21 (p<0.05), while the mean PPBS was reduced significantly from baseline to Day 7(p=0.001), Day 14 to 21 (p=0.01), but insignificant between Day 7 & Day 14 (p=0.2). Conclusion: Dietary regime with Chanadrparabha Vati had quite a significant impact on reducing the PPBS, urine (sugar) levels, and symptomatic relief in type-2 DM patients. But in on other group subjective parameters only Chandraprabha Vati showed fine results. However, in reducing the FBS levels both groups were equally effective.