Review on Cassia Species of Wound Healing & Cytotoxic Activity

The Cassia genus, belonging to the Fabaceae family, encompasses a variety of species traditionally employed in folk medicine. Various studies have highlighted their pharmacological efficacy, particularly in wound healing and anticancer applications. This review consolidates available scientific literature on the wound healing and cytotoxic potential of major Cassia species, their phytoconstituents, and mechanisms of action. Several anthraquinones have been isolated from the seeds of Cassia species. Sennosides, which are well known for their medicinal importance, have been detected in the leaves of the plant. Cassia species are already reported in the ancient ayurvedic literatures and literature survey indicated its use against various skin diseases such as ringworm, eczema, and scabies. Because of the high incidence of skin diseases, especially among the weaker section of the Indian population, it was felt worthwhile undertaking research on this plant. According to ayurveda the leaves and seeds are acrid, laxative, antiperiodic, anthelmintic, ophthalmic, liver tonic, cardiotonic and expectorant. The leaves and seeds are useful in leprosy, ringworm, flatulence, colic, dyspepsia, constipation, cough, bronchitis, cardiac disorders. Cassia species powder made from Cassia species seeds and Cassia species splits are some ancient natural ingredients.