Comparison of the Inhibitory Effect of Different Concentrations of Theobromine Paste on the Growth of Streptococcus mutans as Measured in the Zone of Inhibition

Abstract: Dental caries remains as a public health concern as it is one of the most common diseases that affect children and adult worldwide. Streptococcus mutans, which thrives in the dental plaque biofilm, is considered as the primary contributor to the progression of dental caries. Theobromine is used as a bioactive component since it is known to contain antioxidant, antiviral, and/or antimicrobial property. Theobromine has gained attention as a material for development in dentistry because of its potential role in enamel strengthening and caries prevention. This study aimed to evaluate the effects of different concentrations (0.02%, 0.04%, 0.06%, 0.08%, and 1.00%) of theobromine on the growth of S. mutans. All the different concentrations (0.02%, 0.04%, 0.06%, 0.08%, and 1.00%) of ThP reflected a very active inhibitory inference against S. mutans comparing to the control (0.00%), which only showed an active inhibitory effect. It showed that theobromine can be utilized as a bioactive component to the development of alternative or adjunctive materials that maybe used oral health improvement. Further studies may still be done to find out the best concentration for the formulation of theobromine paste. It is crucial to characterize theobromine’s interactions with various dental materials to fully understand its compatibility, stability, and efficacy in different formulations. Keywords: theobromine, dental caries, Streptococcus mutans, theobromine paste. Title: Comparison of the Inhibitory Effect of Different Concentrations of Theobromine Paste on the Growth of Streptococcus mutans as Measured in the Zone of Inhibition Author: Regine Stelle Rodriguez, Susanne Rodriguez, Noof Al-Subaie, Sung Lyun Lee, Anita Rafiei, Taehoon Kim International Journal of Thesis Projects and Dissertations (IJTPD) Vol. 13, Issue 1, January 2025 - March 2025 Page No: 63-66 Research Publish Journals Website: www.researchpublish.com Published date: 19-February-2025 DOI: https://doi.org/10.5281/zenodo.14892451 Paper Download Link (Source) https://www.researchpublish.com/papers/comparison-of-the-inhibitory-effect-of-different-concentrations-of-theobromine-paste-on-the-growth-of-streptococcus-mutans-as-measured-in-the-zone-of-inhibition