Advances in SNEDDS Tablets: Marketed Formulations and Emerging Technologies for Precision Drug Delivery

Self-nanoemulsifying drug delivery systems (SNEDDS) are transforming the oral delivery of poorly soluble drugs by improving their solubility and bioavailability. Although SNEDDS formulations available in the market have demonstrated favourable results, technological advancements are paving the way for a new era in drug delivery. This review assesses the current state of SNEDDS tablets in the pharmaceutical industry, emphasizing notable formulations and their performance outcomes. It also examines the future potential of SNEDDS and its solid forms and uses High Pressure Homogenisation Technique for conversion, investigating innovative methods like 3D printing, AI-driven formulation optimization, and precision drug delivery. These cutting-edge strategies could personalize treatments, enhance patient adherence, and improve therapeutic results. Additionally, this article discusses the challenges and opportunities that arise from incorporating these technologies into the development of SNEDDS.