Formulation and Evaluation of Effervescent Tablets Using Natural Excipients: A Non-Aqueous Wet Granulation Approach

Effervescent tablets and granules are special dosage forms that contain a medicine plus an effervescent base made of citric acid, tartaric acid, and sodium hydrogen carbonate. When these substances are added to water, they react to release carbon dioxide, which causes effervescence. There are many uses for these granules in daily life. Information on the different ingredients used to make effervescent granules and tablets is provided in this review. Numerous techniques, including the wet method, dry method, fusion method, hot-melt extrusion method, and non-aqueous method, can be used to create effervescent granules. Compression, dry granulation, and wet granulation are methods for creating effervescent pills