Adjuvant Hemostasis in Dental Surgery: Real-Life Practice Data in The Observational, Multi-Center, Prospective, Hemocollagene Clinical Trial

Objective: The current study measured the clinical performance and safety of Hemocollagene when used in its adjuvant hemostasis indication in routine practice by dental surgeons.Methods: This multicenter, prospective observational study conducted within research network ReCOL included 123 patients from 10 hospitals or private practice. Hemocollagene’s 5-minute hemostatic efficacy was differentiated in subgroups of patients according to age and presence of factors influencing coagulation. Device resorption and wound healing were measured after a 31.4-day follow-up.Results: The percentage of patients whose bleeding was stopped within 5 minutes after the use of Hemocollagene was 87.8% (IC95 [82.0; 93.6] %) in the total population. Landry Tissue Healing Index rated 96.3% as good, very good, or excellent after mean 31.4 days (SD: 9.8) post-surgery.Conclusion: Both safety and efficacy of the bovine hemostatic sponges were observed in this real-life study. The good handling of the product ensures a comfortable operation even for bleeding-risk patients.