Review Paper On: Nanostructured Lipid Carriers [NLCs] In Cosmeceutcals

Nanostructured lipid carriers [NLCs] are novel drug delivery system that have gained huge significance in cosmeceuticals industry due to their qualities such as high drug loading capacity, improved stability and increased skin penetration. NLCs has been found to be comparatively more efficient and effective than first generation nanoparticles i.e. SLNs overcoming its drawbacks .These NLCs are solid lipid matrix mixed with a liquid lipid, resulting in a distinct structure allowing better drug entrapment and release characteristics . They have been employed as carriers in cosmeceuticals to improve transport and its performance on the targeted site. NLCs are advanced approach in Targeted Drug Delivery System, having characteristics like better penetration into skin, improved absorption and rapid onset of action including elimination of first pass metabolism. This review article will provide an overview of types of NLCs, its method of preparation, cosmeceuticals benefits on NLC, its current use in cosmetics, interaction with skin and factors affecting permeation of NLC through skin etc. Furthermore, its mechanism of action is also discussed.