Advancements and Future Directions in Nano-Enabled Drug Delivery Systems

The collection of methods used to deliver a medication or pharmacologically active chemical to the target cell in order to treat a disease or other health concern is known as drug delivery. Oral, buccal, rectal, subcutaneous, intranasal, intramuscular, intravenous, pulmonary, and transdermal are the traditional drug delivery methods. These are widely used techniques to treat a variety of medical issues, but they have drawbacks, including sluggish absorption, enzymatic degradation, instability, uncontrolled release, risk of displacement, and discomfort and irritation as side effects, among many others. One of the most effective ways to deliver a medicine in a targeted and sustained manner is by incorporating it into a this nanocarrier overview discusses the uses of nanocarriers, including carbon nanotubes, solid nanoparticles, liposomes, dendrimers, polymeric nanoparticles, polymeric micelles, virus-like nanoparticles, and mesoporous silica nanoparticles. Nucleic acid-based drug delivery systems, cell-based drug delivery systems, self-nano emulsifying drug delivery systems, self-micro emulsifying drug delivery systems, chemical and physical stimuli-based drug delivery systems, nanoneedles, patches, ultrasound drug delivery, and microchip technology are some examples of innovative delivery systems that are designed to overcome the limitations of drug delivery. These systems are commonly referred to as smart drug delivery systems. The fundamentals of drug delivery, pharmacokinetic research, new developments, and potential directions for the drug delivery system are the main topics of this article.