A Comprehensive Review on Advancement in Oral Fast Dissolving Tablet Technologies and Material

Oral dosage form research has advanced significantly, with an emphasis on creating novel conventional dosage forms, particularly for patients who have swallowing issues. In order to increase patient compliance, Fast Dissolving Tablets have emerged as a potential type of tablets that dissolve or disintegrate quickly in the mouth when they come into contact with saliva. This makes the dosage form convenient.This article examines the best features, benefits, and potential drawbacks of FDTs compared to traditional dose forms. FDTs provide quick therapeutic action and rapid dissolution in the mouth, allowing for prompt absorption through the buccal mucosa in 15–120 seconds.These characteristics of the fast-dissolving tablet have been found to be very helpful for elderly and paediatric patients, as well as those who have swallowing difficulties. The benefits of FDTs include improving tongue feel and flavour masking, administering them to patients who are unable to swallow, providing mobile and bedridden patients with comfortable treatment, being easy to administer, and having accurate dosage. FDTs have drawbacks despite their benefits, such as problems with mechanical strength, brittleness, hygroscopicity, and challenges with bitter medications or offensive odours.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-01-15
DOI
https://doi.org/10.5281/zenodo.14649649
Primary Topic
Pharmaceutical studies and practices
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comprehensive Review on Advancement in Oral Fast Dissolving Tablet Technologies and Material

Zenodo (CERN European Organization for Nuclear Research)
Pharmaceutical studies and practices
article

A Comprehensive Review on Advancement in Oral Fast Dissolving Tablet Technologies and Material

article en

Abstract

Oral dosage form research has advanced significantly, with an emphasis on creating novel conventional dosage forms, particularly for patients who have swallowing issues. In order to increase patient compliance, Fast Dissolving Tablets have emerged as a potential type of tablets that dissolve or disintegrate quickly in the mouth when they come into contact with saliva. This makes the dosage form convenient.This article examines the best features, benefits, and potential drawbacks of FDTs compared to traditional dose forms. FDTs provide quick therapeutic action and rapid dissolution in the mouth, allowing for prompt absorption through the buccal mucosa in 15–120 seconds.These characteristics of the fast-dissolving tablet have been found to be very helpful for elderly and paediatric patients, as well as those who have swallowing difficulties. The benefits of FDTs include improving tongue feel and flavour masking, administering them to patients who are unable to swallow, providing mobile and bedridden patients with comfortable treatment, being easy to administer, and having accurate dosage. FDTs have drawbacks despite their benefits, such as problems with mechanical strength, brittleness, hygroscopicity, and challenges with bitter medications or offensive odours.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 49%
Pharmaceutical studies and practices
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