Calculating the level of Uric acid in order to determine the impact of diseases with clinically diagnosed Sepsis

Background and Aim: The definition of acute organ dysfunction and infection, aswell as the data sources used, influence the rates of sepsis and septic shock. Thisinvestigation was therefore carried out to highlight the relationship between morbidityand mortality and hyperuricemia in patients with clinically confirmed sepsis.Materials and Methods: The study included 150 patients in total. Blood samples wereobtained from the patients in order to estimate their uric acid levels. The department ofthe biochemistry and medicine in RKDF Medical College Hospital & Research Center,Jatkhedi, Bhopal, Madhya Pradesh collaborated on the biochemical estimation of theuric acid level.Results: Of the 150 participants in the study, 64 patients (42.7%) had increased uricacid levels, whereas 86 patients (57.3%) had normal uric acid levels. It can be deducedthat patients with type 2 diabetes mellitus were among the study population. 40% is themost prevalent comorbidity. Type 1 and type 2 diabetes, decompensated liver disease,and cerebrovascular accidents were the most common comorbidities among individualswith hyperuricemia. About 36% of research participants who had no comorbidities alsoexperienced sepsis.Conclusion: This study shows that in patients with clinically confirmed sepsis in theintensive care unit, serum uric acid may be utilized as a predictor of death andmorbidity as well as a measure of the severity of the illness. This report suggests moreresearch on a wide foundation for verifying the observations.