Buccal Patches and Natural Polymers: A Synergistic Approach to Drug Delivery

The oral mouth dissolving drug delivery system is regarded as an essential alternative to the peroral route for systemic drug administration since it is considered the most convenient, simple, and safest mode of administration. In terms of flexibility and comfort, mouth dissolving patches may be preferable than mouth dissolving tablets. The goal of this study is to design and characterize a liquorice oral mouth dissolving patch. Oral films made of Xyloglucan, PEG, and glycerine were created by solvent casting. The mechanical characteristics, swelling index, and in vitro drug release were all investigated. For instance, the use of adhesive mucosal preparations has been suggested for the oral delivery of drugs that would prevent swallowing of the dose due to various needs, which include adhesive tablets, adhesive gels, adhesive patches, and various other dosage forms with many combinations of polymers and enhancers of absorption. There is also an increasing interest in natural polymers, and mucoadhesive polymers benefit drug delivery through extended contact time and residence time with mucous membranes.