Oral Disintegrating Film: Comparative Review of Formulation Strategies and Production Challenges

Oral route drug delivery system is still considered as the most convenient and patient friendly drug delivery route. Odf’s are an innovative dosage form that breaks down and dissolves within the oral cavity. Notably, fast-dissolving oral thin films offer a practical solution for a patients such as those in pediatric, as well as geriatric population who struggle with a tablet or hard gelatin capsule ingestion. These rapid- dissolving films are better than fast-disintegrating tablets since the latter have choking and friability issues. This drug delivery technology offers several benefits over traditional fast-disintegrating tablets, including the ability to be used for dysphasic and schizophrenic patients and the capacity to be taken without water due to their quick disintegration and rapid release of medicine in the mouth. This present review provides a brief summary of challenges, composition, formulation methods and evaluation parameters employed for oral disintegrating.