Comparative study of serum cystatin C and urinary creatinine in acute kidney failure patients

Background: Acute kidney failure (AKF), or acute kidney injury (AKI), is a rapid decline in renal function, typically defined by an increase in serum creatinine, a decrease in urine output, or both. AKF can result from a variety of causes, including prerenal, renal, and postrenal factors, and is commonly seen in critically ill patients in intensive care units (ICUs) or those undergoing major surgeries. Material and methods: Comparative study. Individuals that come to Padmashree diagnostic center; Vijayanagar for checkup will be recruited for the study after explanation of the study to the individual; a written informed consent was obtained. Total of 60(n=60) urine and blood samples from healthy individuals(n=30) and CKD patients(n=30)were collected and recruited for the study. The study was approved by institutional review board. Result and discussion: The present study was carried out to assess the status of Cystatin C and Urinary Creatinine levels in renal failure patients. The patients were recruited for the study at Padmashree diagnostics, Department of Clinical laboratory, Vijayanagar, Bangalore. The study initiation started after obtaining the written informed consent.The study population consisted of 30 participants of normal individuals (n=30) and acute renal failure subjects (n=30), mean age of 38.11 ± 4.3 and 54.40 ± 4.6 respectively is suspected to be suffering from CKD. Conclusion: A cross sectional case control study was conducted. It consists a total of 60 subjects(n=60). 30 healthy individuals – Having normal serum creatinine level and 30 Renal failure patients – Having serum Creatinine level >4.0 mg/dl. The subjects were recruited at Padmashree diagnostics, Vijayanagar, Bangalore.