Why normal cells transform into malignant cells

In this paper malignant mutation was studied. Malignant transformation is a multistage process which manipulated with point mutation. Gene activation and tumor suppressor gene inactivation induced by mutations provide strong evidence for the involvement of harmful mechanisms in tumor formation. In the next stage promotion finally resulting in tumor formation. The number of genes that must be activated to convert a normal cell into a malignant cell is unknown at present. In this paper mechanisms a normal cell into a malignant cell transformation were studied by equations which describe genes motion and transition state.