Study of Serum Magnesium in Bronchial Asthma in Maharashtra Population

Background: Bronchial asthma is a disorder defined by its clinical, physio-pathological characteristics. It has shortness of breath episodes that aggravate at night. It impairs physical and social life. Hypomagnesemia is closely associated with bronchial asthma. Method: 250 (two hundred fifty) adult bronchial asthma patients and 250 (one hundred) healthy adult groups were studied and compared. In every patient, 2 ml of venous blood was collected to investigate serum magnesi-um, CBC, ESR, sputum for AFB, and Gram stain for S. mg. were measured by the Elisa kit, chest x-rays were taken, and spirometry was measured to analyse PEFR, FEV, and ECG. Results: The FEV1 in bronchial asthma patients was 45.78 (± 0.36) and 95.42 (± 1.24) in control; the t-test was 60.7, and p < 0.001. Serum magnesium in bronchial asthma patients had 1.66 (± 0.14), and the control group had 2.24 (± 0.05); the t-test was 6.10, and p < 0.41 (p-value was highly significant). Conclusion: It is confirmed that if serum magnesium is reduced, it may aggravate bronchoconstriction in bronchial asthma patients, leading to morbidity and mortality.