Prevalence and antibiotic susceptibility pattern of Uro-pathogens isolated from urine in a tertiary care hospital in Nigeria

Urinary tract infections (UTIs) are one of the most common bacterial infections in humans both in the community and hospital setting. Urinary tract infection (UTI) is the most common health care -associated group of bacterial infection affecting humans in Africa. This study was done to evaluate the frequency of uropathogens isolated from urine and their susceptibility pattern in Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) Bauchi. A total of 373 urine samples from out-patients and hospitalized patients were studied. Samples were inoculated on Cystine Lactose Electolyte-deficient (CLED) agar. 165 isolates were obtained which were further identified by standard Microbiological methods. Antimicrobial Susceptibility pattern was studied by Kirby-Bauer’s disc diffusion method. UTIs were found more common in females 122(73.9%). Among the 165 uropathogens isolated from patients with UTI, the commonest isolate was E. coli (29.1%) followed by Klebsiella pneumoniae (15.8%) with the least Citrobacter spp. 1(0.6%). The overall prevalence of UTI in this study is 44.2%. Multidrug resistance was found to be significantly (P<0.05) more in uropathogens (77%). Monitoring of antimicrobial susceptibility testing are necessary to avoid treatment failure in patients with UTI.