A Systematic Review on Sustained Release Matrix Tablet

The abstract of the document provides an overview of sustained release drug delivery systems. It emphasizes the goal of delivering therapeutic levels of drugs to specific body sites over extended periods. The document discusses the increasing interest in sustained release systems due to high costs of developing new drugs, patent expirations, discovery of new polymers, and improvements in therapeutic efficiency and safety. Various types of matrix tablets, such as hydrophilic, fat-wax, plastic, biodegradable, and mineral matrices, are classified based on their properties and methods of drug release. Advantages, disadvantages, and factors affecting the release from matrix tablets, including physicochemical and biological factors, are also examined. Evaluation tests and criteria for formulating sustained release dosage forms are outlined. The conclusion highlights the benefits of sustained release formulations in enhancing drug efficiency and patient compliance.