A Prospective Study to Evaluate Changes in the Lipid Profile Status of Chronic Kidney Disease Patients on Hemodialysis in Bundelkhand Medical College, Sagar, M.P.

Introduction: A reduction in glomerular filtration rate (GFR) to below 60 ml/min/1.73 m2 for >3 consecutive months associated with multiple etiologies constitutes the definition of chronic kidney disease that can lead to significant lipid disorder which develop primarily from disturbed regulation of high density lipoproteins (HDL) & triglyceride-rich lipoprotein metabolism. Many patients of CKD live on hemodialysis on regular basis. This study was done to know the effect of hemodialysis on the lipid profile of the CKD patients. Background & Methods: This is a prospective observational study conducted in Department of medicine Bundelkhand medical college India, between September 2022 to September 2024 after considering inclusion and exclusion criteria. The lipid profile of 100 eligible patients was analyzed using an autoanalyzer at the central pathology lab at Bundelkhand medical college Sagar . The aim of this research is to study Lipid Profile in CKD patients on Hemodialysis. Results: Our study reported a statistically significant decrease in high-density lipoprotein (HDL) and an increase in triglycerides (TG) and very-low-density lipoprotein (VLDL) levels in CKD patients on hemodialysis. Similarly, total cholesterol and low-density lipoprotein (LDL) were also significantly increased in CKD patients on hemodialysis. Conclusion: Dyslipidemia is an established accompaniment of CKD more so in patients on hemodialysis , so regular monitoring of lipid profile in CKD patients may help in decreasing the progression of the disease and, hence, mortality in CKD patients.