Primary Retroperitoneal Tumors: A Report of 6 Cases

Background: Primary retroperitoneal tumors are rare, accounting for less than 1% of malignancies, and are often diagnosed late due to asymptomatic growth. This study presents six cases managed at CHU Ibn Rochd, Casablanca, to highlight diagnostic and therapeutic challenges.Methods: Six cases (ages 35–67) included liposarcoma, leiomyosarcoma, neurogenic tumors, undifferentiated sarcoma, lymphoma, and desmoid tumors. Treatments involved surgical resection, chemotherapy, and radiotherapy based on tumor type.Results: Complete surgical resection was primary treatment, with adjuvant therapy tailored to histology. Outcomes varied, emphasizing the need for rigorous postoperative surveillance to detect recurrence.Conclusion: A multidisciplinary approach, including early diagnosis, precise surgery, and adjuvant therapy, is essential. Personalized strategies and further research into advanced therapies are needed to improve outcomes in these rare tumors.