ANTIBIOTICS SELECTED TO BE REPURPOSED AS ANTICANCER AGENTS TO COMBAT LUNG CARCINOMA

Identifying new anticancer drugs with unique modes of action has emerged as a serious scientific problem. As a result, the prospect of repurposing antibiotics as anticancer drugs has been investigated. Anticancer antibiotics are substances produced by microorganisms with anticancer activity, principally peptides and anthraquinones, that have a clear and effective effect on preventing cancer from growing uncontrollably, aggressively, and spreading. Anticancer antibiotics include mitomycin, anthracyclines, actinomycin, bleomycin, endiyne and guanorycin. Antibiotics can induce cancer cell death, inhibit cancer cell division, and prevent cancer metastasis. Antibiotics have anticancer properties and may lead cancer cells to die. Despite the introduction of high-throughput sequencing technology in recent years, the possible negative effects of antibiotics on cancer therapy through microbial imbalance have been primarily ignored. Antibiotics in cancer treatment: investigate their potential mechanisms and provide strategies to mitigate the possible adverse effects of antibiotics.