A Review Article on Nipah Virus: Rare and Intractable Disease

An emerging zoonotic virus called Nipah virus (NiV) has been linked to multiple outbreaks that have resulted in high death rates, mostly in South and Southeast Asia[1]. Because spillover events happen occasionally, (HeV) continues to be a major public health concern[2]. The flying fox genus, Pteropus, is a fruit bat species found in many tropical and subtropical regions of the world, and is thought to be a major reservoir of the Nipah virus. There have been losses in the bat's habitat associated with the virus's emergence and zoonotic transmission to humans and livestock[3].. After being discovered for the first time in Malaysia twenty years ago, outbreaks have since occurred throughout South and Southeast Asia. It is extremely deadly and causes severe neurological and respiratory disease. It is extremely contagious and can infect animals or other people, which allows it to spread throughout the communit[4]. Variations exist in the clinical and epidemiological characteristics of distinct virus strains. Numerous techniques, such as molecular, virological, immune histochemical, and serological methods, can be used to make the diagnosis[5]. The identification of broad- spectrum antivirals requires both antibody-body drugs and a focus on small interfering RNAs (siRNAs). Due to the high pathogenicity of NiV in humans and the lack of treatments or vaccines to combat this illness, researchers from all over the world are focusing on creating effective NiV treatment plans and vaccines