Parenteral Iron Sucrose Transfusion in Pregnant Women with Iron Deficiency Anaemia and its Outcome
Introduction: Iron deficiency anaemia (IDA) is common in pregnancy, characterized by reduced red blood cells or haemoglobin due to low iron levels. Pregnancy increases iron demand to support fetal development and the mother’s blood volume. Insufficient iron intake or absorption can lead to IDA, causing complications like low birth weight, postpartum bleeding, and maternal mortality. Iron Sucrose, an IV preparation, due to its efficacy and safety profile become widely used in patients unable to take oral iron preparation. Materials and Methodology: This was a prospective, observational study conducted in the obstetrics and gynecology department of Parul Sevashram Hospital over four months. A total of 30 pregnant women with IDA undergoing parenteral iron sucrose therapy were enrolled. Haemoglobin level and its severity were measured on 4th and 8th weeks from last dose of iron sucrose. Data were recorded in predesigned case record forms, entered in Microsoft Excel, and analyzed using appropriate statistical methods. Results: In present study most participants were aged 26-30 years, with a majority having an education level of 1st to 9th grade and being housewives. The mean age was 25.2 years. There was significant increase in haemoglobin levels from 8.11 ± 0.88 gm/dL at baseline to 10.28 ± 0.66 gm/dL after eight weeks (p<0.001). Haemoglobin levels increased significantly across all severity levels of anaemia (mild, moderate, severe) over the eight weeks. Adverse drug reactions included one case of anaphylactic reaction and two cases of skin rashes. Conclusion: The study shows that intravenous iron sucrose is a safe and effective treatment for IDA in pregnant women. Haemoglobin levels significantly increased over eight weeks, with 20% of participants reaching normal levels. Adverse reactions were minimal. These findings support intravenous iron sucrose as a reliable option, especially for those intolerants to oral supplements and reducing pregnancy-related anaemia complications.
Institutions
- Dharmsinh Desai University (IN)
- Parul University (IN)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-11-06
- DOI
- https://doi.org/10.5281/zenodo.14245156
- Citations
- 1
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.45