Transdermal Drug Delivery System: A Review

The development of the transdermal drug delivery system aimed to address the issues related to oral drug consumption.These systems usually involve applying medicated adhesive patches on skin to deliver medication directly into the bloodstream for targeted treatment. One significant advantage of these patches is their ability to release medication in a controlled manner , either through a porous membrane over a medication reservoir or via melting by body temperature, thin medication layers within the adhesive.This article seeks to explain the pros, cons, and important components of the transdermal drug patches , including polymers, permeation enhancers, backing laminates, and adhesives. Assessment criteria cover various aspects like chemical properties, adhesive effectiveness, and results from in vivo and in vitro studies. Recent advances in this area show a growing interest in transdermal delivery due to its potential to minimize side effects when compared to the other methods of administration.