The Outcome of ATT In Microbiologically confirmed EPTB-HIV Patients in Tertiary Care Hospital - A Retrospective Study

Background: Management of tuberculosis is challenging in HIV/TB co-infected individuals. Antitubercular therapy can minimize morbidity and mortality. Novel diagnostic methods such as CBNAAT can be useful in certain forms of extrapulmonary tuberculosis. In developing countries like India, the percentage of EPTB cases is between 15-20% which has increased to more than 50% among HIV co infected patients suggesting immune status of the host being a major risk factor of Extra Pulmonary Tuberculosis. Methods: We conducted a retrospective study among EPTB-HIV co-infected patients enrolled in Pulmonology department at Sri Venkateshwara Ramnarayan Ruia Government General Hospital, tertiary care teaching hospital, Tirupati. Results & Conclusion: This study has shown that EPTB is an important cause of admission in hospitals due to LNTB. ATT was found to be effective in EPTB-HIV, so it should be strengthened, to control HIV-TB epidemic. The success rate of TB treatment among those patients in this study was 64.7% whereas low mortality rates are observed.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-13
DOI
https://doi.org/10.5281/zenodo.15018130
Primary Topic
Advanced Wireless Communication Technologies
Type
article
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article

The Outcome of ATT In Microbiologically confirmed EPTB-HIV Patients in Tertiary Care Hospital - A Retrospective Study

Zenodo (CERN European Organization for Nuclear Research)
Advanced Wireless Communication Technologies
article

The Outcome of ATT In Microbiologically confirmed EPTB-HIV Patients in Tertiary Care Hospital - A Retrospective Study

article en

Abstract

Background: Management of tuberculosis is challenging in HIV/TB co-infected individuals. Antitubercular therapy can minimize morbidity and mortality. Novel diagnostic methods such as CBNAAT can be useful in certain forms of extrapulmonary tuberculosis. In developing countries like India, the percentage of EPTB cases is between 15-20% which has increased to more than 50% among HIV co infected patients suggesting immune status of the host being a major risk factor of Extra Pulmonary Tuberculosis. Methods: We conducted a retrospective study among EPTB-HIV co-infected patients enrolled in Pulmonology department at Sri Venkateshwara Ramnarayan Ruia Government General Hospital, tertiary care teaching hospital, Tirupati. Results & Conclusion: This study has shown that EPTB is an important cause of admission in hospitals due to LNTB. ATT was found to be effective in EPTB-HIV, so it should be strengthened, to control HIV-TB epidemic. The success rate of TB treatment among those patients in this study was 64.7% whereas low mortality rates are observed.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 57%
Advanced Wireless Communication Technologies
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The Outcome of ATT In Microbiologically confirmed EPTB-HIV Patients in Tertiary Care Hospital - A Retrospective Study · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS