Association of Metabolic Syndrome with Coronary Artery Disease in Andhra Pradesh Population

Background: Metabolic syndrome is defined to investigate the cardiovascular effects of metabolic syndrome. Method: 150 metabolic syndrome patients having positive angiography of CAD was compared with 150 non-Mets volunteers (controlled). Blood investigation, i.e., lipid profile, insulin levels, IL-6, TNF-α, Hs-CRP, HOME-IR, Quickie, and angiological findings showing single vessel disease, double vessel disease, and triple vessel diseases, were analyzed. BMI, HTN, and DM were also noted. Results: Comparison of biochemical analysis in metabolic syndrome (MS) with non-metabolic syndrome (Non-MS): TG, HDL, VLDL, and LDL had a significant p value (p<0.001). In the present study, 23 (15.3) MS groups had type-II DM, and 120 (80%) HTN were noted, and 12 (8%) had type-II DM, and 18 (12%) HTN was observed in the non-MS group. A comparative study of anthropometric, biochemical, and inflammatory bi-omarkers had a significant p value (p<0.001). Conclusion: In the present pragmatic study there is a strong correlation of metabolic syndrome (MS) with cor-onary artery disease (CHD). It will help the clinician to treat such patients efficiently to avoid morbidity and mortality.